Berberine – Better Immune System And Metabolism
Diabetes. Berberine seems to slightly reduce blood sugar levels in people with diabetes. Also, some early research shows that taking 500 mg of berberine 2-3 times daily for up to 3 months might control blood sugar as effectively as metformin or rosiglitazone.
High levels of cholesterol or other fats (lipids) in the blood (hyperlipidemia). Berberine might help lower cholesterol levels in people with high cholesterol. Taking berberine for up to 2 years seems to reduce total cholesterol, low-density lipoprotein (LDL or “bad”) cholesterol, and triglyceride levels in people with high cholesterol. When compared with standard cholesterol-lowering medications, berberine appears to cause similar changes in total cholesterol, LDL cholesterol, and high-density lipoprotein (HDL or “good”) cholesterol, and it might be better at reducing triglyceride levels.
High blood pressure. Taking 0.9 grams of berberine per day along with the blood pressure-lowering drug amlodipine reduces systolic blood pressure (the top number) and diastolic blood pressure (the bottom number) better than taking amlodipine alone in people with high blood pressure.
A hormonal disorder that causes enlarged ovaries with cysts (polycystic ovary syndrome or PCOS). Research shows that berberine can lower blood sugar, improve cholesterol and triglyceride levels, reduce testosterone levels, and lower waist-to-hip ratio in women with PCOS. Berberine may even lower blood sugar levels similar to metformin and may improve cholesterol levels better than metformin. It is unclear if berberine increases pregnancy rates or live birth rates in women with PCOS.
Insufficient Evidence for
Burns. Early research shows that applying an ointment that contains berberine and beta-sitosterol can treat second-degree burns as effectively as conventional treatment with silver sulfadiazine.
An infection of the intestines that causes diarrhea (cholera). Some early research shows that taking berberine sulfate can decrease diarrhea by a small amount in people with cholera. However, berberine does not seem to improve the effects of the antibiotic tetracycline in treating diarrhea related to cholera infection.
Non-cancerous growths in the large intestine and rectum (colorectal adenoma). Early research shows that taking berberine for 2 years seems to prevent regrowth of colorectal adenomas in people who have already been treated for these growths.
Heart failure and fluid build up in the body (congestive heart failure or CHF). Early research shows that berberine can reduce some of the symptoms and lower the death rate in some people with congestive heart failure.
Heart disease. Research shows that taking a specific product containing berberine and other ingredients for 3 months lowers cholesterol levels in people with heart disease who had a procedure called a percutaneous intervention (PCI). This product seems to lower cholesterol levels more than the standard medication ezetimibe, which is used to lower cholesterol. Also taking this product in combination with low doses of medicines called “statins” seems to work better than taking low-dose statins alone. It’s unclear if the effects of this product are due to berberine, other ingredients, or the combination. It’s also unknown whether this product reduces the risk of major adverse heart-related events in people with heart disease.
Diarrhea. Some early research shows that taking berberine sulfate can decrease diarrhea in people with an E. coli infection.
A group of eye disorders that can lead to vision loss (glaucoma). Early research shows that using eye drops containing berberine and tetrahydrozoline for does not reduce eye pressure in people with glaucoma better than eye drops containing tetrahydrozoline alone.